| The Beacon of Downtown HoustonHouston | Form 990 | $4,911,987FY2024 |
| Uvalde Emergency Medical Services IncUvalde | Form 990 | $4,862,631FY2025 |
| San Antonio Eye BankSan Antonio | Form 990 | $4,791,422FY2025 |
| Texas Lions Camp IncKerrville | Form 990 | $4,789,519FY2025 |
| American Religious Town Hall Meeting IncorporatedGrand Prairie | Form 990 | $4,752,077FY2024 |
| Friends for LifeWaco | Form 990 | $4,737,075FY2025 |
| Camp County Ambulance Service CorporationPittsburg | Form 990 | $4,693,666FY2025 |
| North Texas Rehabilitation CenterWichita Falls | Form 990 | $4,675,936FY2025 |
| Childrens Association for Maximum Potential IncSan Antonio | Form 990 | $4,673,782FY2025 |
| Medical Center of the AmericasfoundationEl Paso | Form 990 | $4,651,202FY2025 |
| Christus Spohn Health System Development FoundationCorpus Christi | Form 990 | $4,532,624FY2025 |
| Jefferson County Clinical Services IncAustin | Form 990 | $4,500,000FY2025 |
| Scott & White Emergency Medical ServicesDallas | Form 990 | $4,486,752FY2025 |
| Harris County Hospital District FoundationBellaire | Form 990 | $4,486,747FY2025 |
| Planned Parenthood San AntonioSan Antonio | Form 990 | $4,451,663FY2024 |
| Migrant Clinicians Network IncAustin | Form 990 | $4,418,992FY2024 |
| Sunshine Kids FoundationHouston | Form 990 | $4,313,330FY2025 |
| Granbury Hood County Emergency Medical Services IncGranbury | Form 990 | $4,310,428FY2024 |
| Texas Palliative CareTyler | Form 990 | $4,270,595FY2024 |
| St John Paul II Life CenterAustin | Form 990 | $4,249,016FY2025 |
| North Texas Addiction Counseling and Education IncFort Worth | Form 990 | $4,238,482FY2024 |
| Temple Memorial Pediatric Center IncTexarkana | Form 990 | $4,234,806FY2025 |
| Runningwater Draw Care Center IncOlton | Form 990 | $4,018,344FY2024 |
| Bexar County Community Health CollaborativeSan Antonio | Form 990 | $4,017,019FY2024 |
| Pedi-Ortho Health CorporationDallas | Form 990 | $3,941,285FY2025 |
| Permian Basin Womens Resource Center IncMidland | Form 990 | $3,936,913FY2024 |
| Fundacion Latinoamericana de Accion Social IncHouston | Form 990 | $3,887,614FY2024 |
| Fairfield Ambulance Service IncFairfield | Form 990 | $3,647,313FY2024 |
| Piney Woods Regional Advisory CouncilTyler | Form 990 | $3,591,660FY2025 |
| UT Health San Antonio Regional Physician NetworkSan Antonio | Form 990 | $3,476,507FY2025 |
| Angleton Area Emergency Medical Corps IncAngleton | Form 990 | $3,466,232FY2024 |
| Permian Basin Rehabilitation Center for Crippled Children and AdultsOdessa | Form 990 | $3,312,040FY2024 |
| Aggieland Pregnancy OutreachCollege Station | Form 990 | $3,303,740FY2024 |
| Texas Health InstituteAustin | Form 990 | $3,249,085FY2024 |
| Willacy County E M S IncRaymondville | Form 990 | $3,229,699FY2024 |
| American Botanical CouncilAustin | Form 990 | $3,168,766FY2025 |
| Pro-ActionEl Paso | Form 990 | $3,154,678FY2025 |
| Lake Jackson Emergency Medical ServicesLake Jackson | Form 990 | $3,104,527FY2025 |
| Cactus Health Services IncFort Stockton | Form 990 | $3,100,287FY2025 |
| Texas EMS Trauma & Acute Care FoundationAustin | Form 990 | $3,069,831FY2024 |
| Baylor Oral Health FoundationDallas | Form 990 | $3,062,151FY2025 |
| Heal the City Free ClinicAmarillo | Form 990 | $3,051,125FY2025 |
| Arlington Pregnancy Center IncArlington | Form 990 | $3,048,384FY2024 |
| Rising TogetherLometa | Form 990 | $3,040,383FY2024 |
| East Texas Mental Health IncorporatedTyler | Form 990 | $2,979,228FY2025 |
| Ruthe B Cowl Rehabilitation CenterLaredo | Form 990 | $2,958,804FY2024 |
| Clear Lake Emergency Medical CorpsDickinson | Form 990 | $2,947,339FY2025 |
| Corpus Christi Pregnancy Center IncCorpus Christi | Form 990 | $2,887,153FY2024 |
| Panhandle Regional Advisory Council Trauma Service Area aCanyon | Form 990 | $2,865,468FY2025 |
| Texoma Regional Blood CenterSherman | Form 990 | $2,795,471FY2025 |