| Habitat for Humanity International IncLancaster | Form 990-N | No figure |
| The Marion Clothing Closet IncMarion | Form 990-N | No figure |
| PTA S C CongressBoiling Springs | Form 990-EZ | $43,880FY2025 |
| Mental Health America of South CarolinaSumter | Form 990-N | No figure |
| Horry County K-12 FoundationMyrtle Beach | Form 990 | $43,174FY2024 |
| United Way of Edgefield County IncEdgefield | Form 990-N | No figure |
| PTA South Carolina CongressTaylors | Form 990-EZ | $42,152FY2026 |
| Auxiliary of Volunteers of Prisma Health Baptist HospitalColumbia | Form 990 | $41,602FY2025 |
| Anderson County Womans Club IncAnderson | Form 990-N | No figure |
| PTA South Carolina CongressGreer | Form 990-EZ | $40,821FY2025 |
| Lake City Concert SeriesLake City | Form 990-N | No figure |
| Kensington Elementary School PTAGeorgetown | Form 990-EZ | $38,934FY2025 |
| Parent Booster USA IncNorth Charleston | Form 990-N | No figure |
| Camden Bulldog ClubCamden | Form 990-EZ | $38,788FY2025 |
| Columbus Parker Track ClubLancaster | Form 990-N | No figure |
| Rock Springs Fire Department 1Belton | Form 990-N | No figure |
| Junior Service LeagueOrangeburg | Form 990-EZ | $37,217FY2025 |
| Mental Health America of South CarolinaFlorence | Form 990-N | No figure |
| Pompion Hill Chapel Foundation IncHuger | Form 990-N | No figure |
| Williamsburgh Historical SocietyKingstree | Form 990-N | No figure |
| Inspire Abilities Foundation IncAnderson | Form 990-N | No figure |
| Troop Appreciation Fishing Fund FoundationChapin | Form 990-N | No figure |
| South Carolina Congress of Parents and TeachersSummerville | Form 990-EZ | $34,696FY2025 |
| South Carolina Congress of Parents and TeachersGreer | Form 990-EZ | $34,540FY2025 |
| PTA South Carolina CongressSummerville | Form 990-EZ | $33,358FY2026 |
| Fripp Island Volunteer RescueFripp Island | Form 990-EZ | $33,275FY2025 |
| Family Career and Community Leaders of America IncGresham | Form 990-N | No figure |
| Darlington Downtown Revitalization AssociationDarlington | Form 990-N | No figure |
| General Federation of Womens Clubs of South CarolinaColumbia | Form 990-N | No figure |
| Taylors Youth Assoc IncTaylors | Form 990-N | No figure |
| Rotary InternationalGilbert | Form 990-N | No figure |
| South Carolina Congress of Parents and TeachersSummerville | Form 990-EZ | $31,728FY2025 |
| PTA South Carolina CongressLexington | Form 990-N | No figure |
| Volunteer Rescue Squad of Myrtle Beach IncMyrtle Beach | Form 990-N | No figure |
| The Hebrew Benevolent Society of Charleston South CarolinaCharleston | Form 990-EZ | $29,657FY2024 |
| Edgefield County School District Education FoundationEdgefield | Form 990-N | No figure |
| Florence Regional Arts Alliance IncFlorence | Form 990-N | No figure |
| Stone Soup Storytelling InstituteWoodruff | Form 990-N | No figure |
| PTA South Carolina CongressGreer | Form 990-EZ | $26,206FY2025 |
| Aiken Choral Society IncAiken | Form 990-N | No figure |
| Good UnlimitedColumbia | Form 990-N | No figure |
| Friends of the Greenwood County Libraries IncGreenwood | Form 990-N | No figure |
| Sandy Springs Volunteer Fire and Rescue UnitLaurens | Form 990-N | No figure |
| Brothers & Sisters of Aiken CountyAiken | Form 990-N | No figure |
| National Society of the Daughters of the American RevolutionClemson | Form 990-EZ | $24,080FY2025 |
| PTA South Carolina CongressSummerville | Form 990-N | No figure |
| Garden Club Council of Greater ColumbiaColumbia | Form 990-N | No figure |
| Cherokee County Literacy AssociationGaffney | Form 990-N | No figure |
| South Carolina Association for the Education of Young ChildrenDrayton | Form 990-N | No figure |
| National Society of the Sons of the American RevolutionMount Pleasant | Form 990-N | No figure |