| United Way of Forsyth County IncWinston-Salem | Form 990 | $9,587,732FY2025 |
| Habitat for Humanity Orange CountyChapel Hill | Form 990 | $9,248,390FY2025 |
| Lifespan IncorporatedCharlotte | Form 990 | $9,160,771FY2025 |
| Boys & Girls Clubs of the Coastal Plain IncWinterville | Form 990 | $8,913,327FY2024 |
| Foundation for Health Leadership and Innovation IncorporatedCary | Form 990 | $8,908,242FY2025 |
| Davidson-Davie Community College Foundation IncLexington | Form 990 | $8,768,943FY2025 |
| Habitat for Humanity of Durham IncDurham | Form 990 | $8,468,889FY2024 |
| Oe Enterprises IncorporatedHillsborough | Form 990 | $8,434,816FY2025 |
| Twin Rivers Opportunities IncNew Bern | Form 990 | $8,199,630FY2025 |
| Eastern Area Health Education Center IncGreenville | Form 990 | $8,072,756FY2025 |
| North Carolina Advanced Energy CorporationRaleigh | Form 990 | $7,935,080FY2024 |
| The Enola Group IncMorganton | Form 990 | $7,934,672FY2025 |
| Action for Child Protection IncMint Hill | Form 990 | $7,695,650FY2025 |
| Special Olympics North Carolina IncMorrisville | Form 990 | $7,463,638FY2025 |
| Habitat for Humanity International IncAberdeen | Form 990 | $7,355,209FY2025 |
| Black River Health Services IncBurgaw | Form 990 | $7,335,273FY2025 |
| The North Carolina Community Action AssociationRaleigh | Form 990 | $7,257,311FY2024 |
| Contemporary Science CenterDurham | Form 990 | $7,236,752FY2025 |
| Roanoke Island Historical Association IncManteo | Form 990 | $7,185,556FY2024 |
| Disability Rights North CarolinaRaleigh | Form 990 | $6,859,243FY2025 |
| Resources Exchange AssociationBurlington | Form 990 | $6,847,867FY2024 |
| Boys & Girls Clubs of SoutheasternWilmington | Form 990 | $6,776,651FY2025 |
| East Carolina University Medical & Health Sciences Foundation IncGreenville | Form 990 | $6,762,791FY2025 |
| National Institute of Minority Economic DevelopmentDurham | Form 990 | $6,532,015FY2024 |
| Mecklenburg Aquatic Club IncCharlotte | Form 990 | $6,433,499FY2025 |
| Fairview Volunteer Fire Department Incorporated Buncombe CountyFairview | Form 990 | $6,431,838FY2025 |
| Burke United Christian MinistriesMorganton | Form 990 | $6,365,471FY2025 |
| Carolina Farm Stewardship AssociationPittsboro | Form 990 | $6,213,161FY2024 |
| Randolph Community Service IncRandleman | Form 990 | $6,200,050FY2025 |
| Quality Home Care Services IncCharlotte | Form 990 | $6,154,455FY2025 |
| Macon Citizens for the Handicapped IncFranklin | Form 990 | $5,990,095FY2025 |
| The North Carolina Public Television Foundation IncResearch Triangle Park | Form 990 | $5,882,958FY2025 |
| Daniel Jonathan Stowe ConservancyBelmont | Form 990 | $5,855,609FY2025 |
| Transylvania Habitat for Humanity IncBrevard | Form 990 | $5,840,820FY2025 |
| North Carolina Business Committee for Education IncRaleigh | Form 990 | $5,663,302FY2024 |
| Our Community Hospital IncScotland Neck | Form 990 | $5,632,938FY2025 |
| The Family Violence Prevention Center IncRaleigh | Form 990 | $5,624,032FY2025 |
| Baptist Missions to Forgotten PeoplesKernersville | Form 990 | $5,604,095FY2025 |
| Positive Childhood Alliance North CarolinaMorrisville | Form 990 | $5,583,169FY2025 |
| Veterans Bridge Home IncCharlotte | Form 990 | $5,561,365FY2024 |
| National MPS Society IncDurham | Form 990 | $5,554,247FY2025 |
| Big South Conference IncCharlotte | Form 990 | $5,554,179FY2025 |
| Feed the Hunger IncGreensboro | Form 990 | $5,537,252FY2024 |
| Remnant of Israel IncCharlotte | Form 990 | $5,509,461FY2024 |
| Legacy Human Services IncHenderson | Form 990 | $5,494,720FY2025 |
| Veteran Golfers AssociationPinehurst | Form 990 | $5,490,965FY2024 |
| Make a Wish Foundation of Eastern North Carolina IncRaleigh | Form 990 | $5,469,684FY2025 |
| Eblen CharitiesAsheville | Form 990 | $5,462,134FY2024 |
| John Locke Foundation IncRaleigh | Form 990 | $5,424,918FY2025 |
| Eastern Carolina Young Mens Christian Association IncNew Bern | Form 990 | $5,420,402FY2025 |