| Aerospace CorporationChantilly | Form 990 | $1,623,067,000FY2025 |
| Noblis IncReston | Form 990 | $614,468,693FY2025 |
| Institute for Defense AnalysesAlexandria | Form 990 | $344,675,047FY2025 |
| American Type Culture CollectionManassas | Form 990 | $198,027,310FY2024 |
| Associated Universities IncVienna | Form 990 | $145,098,658FY2025 |
| Analytic Services IncArlington | Form 990 | $142,473,079FY2025 |
| US Civilian Research and Development FoundationArlington | Form 990 | $73,586,507FY2024 |
| American Society of Civil EngineersReston | Form 990 | $58,896,001FY2025 |
| Amazon Conservation TeamFalls Church | Form 990 | $41,839,038FY2025 |
| Virginia Innovation Partnership CorporationHerndon | Form 990 | $33,814,047FY2025 |
| Noblereach FoundationTysons | Form 990 | $30,312,249FY2024 |
| Commonwealth Center for Advanced ManufacturingDisputanta | Form 990 | $23,287,216FY2025 |
| National Society of Black EngineersAlexandria | Form 990 | $22,741,085FY2025 |
| Virginia Health InformationRichmond | Form 990 | $13,708,032FY2025 |
| American Association of Physicists in MedicineAlexandria | Form 990 | $12,033,446FY2024 |
| Foundation for Energy Security and Innovation IncArlington | Form 990 | $10,629,764FY2025 |
| The National Council of Teachers of Mathematics-Incorporated-Reston | Form 990 | $10,428,676FY2025 |
| Center for Open ScienceCharlottesville | Form 990 | $10,217,166FY2024 |
| GeoscienceworldMcLean | Form 990 | $10,028,003FY2025 |
| Ocean Visions IncLeesburg | Form 990 | $8,313,870FY2024 |
| National Institute of Aerospace AssociatesHampton | Form 990 | $7,550,232FY2025 |
| Institute of NavigationManassas | Form 990 | $6,781,475FY2026 |
| Center for Excellence in EducationMcLean | Form 990 | $4,218,108FY2024 |
| Korean-American Scientists and Engineers Association IncVienna | Form 990 | $3,928,701FY2025 |
| Zcash FoundationMcLean | Form 990 | $3,769,087FY2024 |
| Corporation for National Research InitiativesReston | Form 990 | $3,094,378FY2024 |
| American Institute of Biological Sciences IncHerndon | Form 990 | $2,864,258FY2024 |
| National Security Space Association IncArlington | Form 990 | $2,475,426FY2024 |
| International Society for Computational Biology IncLeesburg | Form 990 | $2,444,199FY2024 |
| National Society of Black PhysicistsArlington | Form 990 | $2,343,741FY2025 |
| American Society of Naval EngineersAlexandria | Form 990 | $2,340,059FY2023 |
| Global Cold Chain FoundationArlington | Form 990 | $2,255,015FY2024 |
| BGH FoundationFredericksburg | Form 990 | $2,237,108FY2024 |
| Concrete Advancement Foundation IncAlexandria | Form 990 | $2,111,884FY2025 |
| Mineralogical Society of AmericaChantilly | Form 990 | $1,718,799FY2024 |
| Building Change IncRichmond | Form 990 | $1,703,145FY2025 |
| Foundation for Earth Science Information PartnersVienna | Form 990 | $1,448,963FY2025 |
| Society for Industrial Microbiology and BiotechnologyFairfax | Form 990 | $1,367,211FY2024 |
| American Astronautical Society IncSpringfield | Form 990 | $1,043,824FY2024 |
| Center for Cyber Safety and EducationAlexandria | Form 990 | $918,922FY2025 |
| Mid-Atlantic Research Infrastructure AllianceBlacksburg | Form 990 | $820,106FY2025 |
| National Association of Biology Teachers IncWarrenton | Form 990 | $789,226FY2025 |
| Korea Us Quantum Technology Cooperation CenterVienna | Form 990 | $729,934FY2024 |
| World Ocean CouncilVienna | Form 990 | $721,867FY2024 |
| Virginia Biosciences Health Research CorporationRichmond | Form 990 | $676,190FY2025 |
| Fisheye Collaborative IncArlington | Form 990 | $650,358FY2025 |
| Virginia Academy of ScienceRichmond | Form 990 | $646,502FY2025 |
| Fed Tech CaresGreat Falls | Form 990 | $641,433FY2025 |
| Pallet FoundationAlexandria | Form 990 | $636,061FY2024 |
| International Union of Geological SciencesReston | Form 990 | $630,031FY2025 |