| Chromosome 18 Registry and Research SocietySan Antonio | Form 990 | $795,557FY2025 |
| Santa Anna FoundationSanta Anna | Form 990 | $793,132FY2024 |
| South Texas Alliance for OrphansBoerne | Form 990 | $789,176FY2025 |
| North East Educational Foundation IncSan Antonio | Form 990 | $788,331FY2025 |
| Chamberlain BalletPlano | Form 990 | $788,305FY2025 |
| Texas Youth CampWashington | Form 990 | $781,174FY2024 |
| Association for Supervisor and Curriculum DevelopmentAustin | Form 990 | $780,905FY2023 |
| Langtry Village IncMidland | Form 990 | $780,624FY2025 |
| Pregnancy Help Center IncKaty | Form 990 | $780,217FY2025 |
| Future Farmers of AmericaHouston | Form 990 | $779,518FY2025 |
| Garland Isd Education FoundationGarland | Form 990 | $779,472FY2025 |
| United Way of Grayson County IncSherman | Form 990 | $776,405FY2025 |
| American Planning AssociationAustin | Form 990 | $773,659FY2025 |
| Azteca Economic Development and Preservation CorporationLaredo | Form 990 | $773,319FY2024 |
| Urban-15 GroupSan Antonio | Form 990 | $772,902FY2025 |
| Child Welfare Alliance of Calhoun County IncPort Lavaca | Form 990 | $771,955FY2025 |
| Texas Bandmasters Association IncSan Antonio | Form 990 | $769,670FY2025 |
| Texas Historical FoundationDallas | Form 990 | $767,579FY2025 |
| Paralyzed Veterans of AmericaCrosby | Form 990 | $765,521FY2025 |
| Big Brothers Big Sisters of the Permian Basin IncMidland | Form 990 | $765,390FY2025 |
| Bexar County Medical Library AssociationSan Antonio | Form 990 | $762,804FY2024 |
| Blackland Community Development CorporationAustin | Form 990 | $761,964FY2024 |
| South Texas Youth Soccer AssociationSpring | Form 990 | $761,846FY2026 |
| Messianic Jewish Family Bible Society IncPantego | Form 990 | $761,690FY2024 |
| Keep Pearland BeautifulPearland | Form 990 | $756,430FY2025 |
| PTA Texas CongressHouston | Form 990 | $756,033FY2026 |
| I Am a Golfer FoundationDallas | Form 990 | $756,027FY2024 |
| Tim Lee MinistriesGarland | Form 990 | $750,899FY2024 |
| Gulf Coast Leadership Council IncHouston | Form 990 | $750,213FY2024 |
| Technology Student AssociationCarthage | Form 990 | $745,528FY2025 |
| Humane Society of Dallas CountyDallas | Form 990 | $743,230FY2025 |
| Marble Falls Area Volunteer Fire Department IncMarble Falls | Form 990 | $742,429FY2025 |
| The Hillel at Texas A & MCollege Station | Form 990 | $742,334FY2026 |
| The Boys & Girls Club of the Big PinesMarshall | Form 990 | $737,835FY2024 |
| Preservation Texas IncAustin | Form 990 | $735,359FY2024 |
| Howard County Fair Association IncBig Spring | Form 990 | $734,979FY2025 |
| Evelyns Park ConservancyBellaire | Form 990 | $734,447FY2024 |
| Guadalupe-Parkway Neighborhood Center of Lubbock IncLubbock | Form 990 | $734,016FY2025 |
| Pro Life of Navarro CountyCorsicana | Form 990 | $732,213FY2024 |
| Region Vi Chapter of Voluntary Protection Programs ParticipantsHunt | Form 990 | $728,272FY2025 |
| Tyler Catholic School FoundationTyler | Form 990 | $727,970FY2024 |
| Maurice Barnett Geriatric Wellness Center IncPlano | Form 990 | $727,831FY2025 |
| International Pediatric Research Foundation IncThe Woodlands | Form 990 | $726,888FY2024 |
| Hidden Acres IncKaufman | Form 990 | $726,594FY2025 |
| PTA Texas CongressHouston | Form 990 | $725,005FY2026 |
| Boy Scouts of AmericaWichita Falls | Form 990 | $722,808FY2025 |
| KidlinksDallas | Form 990 | $722,672FY2024 |
| Oasis InstituteSan Antonio | Form 990 | $720,630FY2025 |
| North Ellis County Outreach IncRed Oak | Form 990 | $716,923FY2024 |
| Agape Raymondville Properties IncSan Antonio | Form 990 | $709,629FY2025 |