| Harbor Historical Association of GeorgetownGeorgetown | Form 990 | $741,037FY2024 |
| BC CorpGreenville | Form 990 | $740,538FY2024 |
| South Carolina First Steps to School Readiness Board of TrusteesGreenwood | Form 990 | $737,505FY2025 |
| Summerville High School Athletic ClubSummerville | Form 990 | $727,230FY2025 |
| Supporters of School District No 1 IncCampobello | Form 990 | $720,692FY2025 |
| Folds of Honor FoundationSimpsonville | Form 990 | $690,332FY2025 |
| Compass of Carolina IncGreenville | Form 990 | $684,418FY2024 |
| The Foothills Agricultural Resources and Marketing CenterSeneca | Form 990 | $683,308FY2024 |
| South Carolina First Steps to School Readiness Board of TrusteesLamar | Form 990 | $663,523FY2025 |
| South Carolina First Steps to School Readiness Board of TrusteesGreenwood | Form 990 | $657,118FY2025 |
| South Carolina First Steps to School Readiness Board of TrusteesGreenwood | Form 990 | $643,940FY2025 |
| Orangeburg Calhoun Technical College Foundation IncorporatedOrangeburg | Form 990 | $641,852FY2025 |
| Bel-Aire Community PartnersGreenville | Form 990 | $641,036FY2025 |
| International Town & Gown AssociationClemson | Form 990 | $636,253FY2025 |
| Sumter Rotary Club Scholarship FundSumter | Form 990 | $624,538FY2025 |
| South Carolina First Steps to School Readiness Board of TrusteesGreenwood | Form 990 | $611,979FY2025 |
| Legacy AdvancementGreenville | Form 990 | $608,039FY2024 |
| Food for the Soul - Kershaw County IncCamden | Form 990 | $602,556FY2024 |
| Fort Mill District Band Booster Club IncFort Mill | Form 990 | $600,926FY2026 |
| Angels ClubColumbia | Form 990 | $600,797FY2025 |
| Feed & Seed CoGreenville | Form 990 | $599,669FY2024 |
| Flourish Adoption Ministries IncGreenville | Form 990 | $586,153FY2025 |
| Rape Crisis Center Serving Horry and Georgetown CountiesMyrtle Beach | Form 990 | $583,560FY2025 |
| Saint James Day School IncCharleston | Form 990 | $582,508FY2025 |
| Chiefs Athletic Booster ClubLittle River | Form 990 | $579,009FY2025 |
| Coastal School Ministries IncMyrtle Beach | Form 990 | $574,025FY2025 |
| Technical College of the Lowcountry Foundation IncorporatedBeaufort | Form 990 | $571,466FY2025 |
| Greenville High Red Raider Sports Booster Club IncGreenville | Form 990 | $556,496FY2025 |
| South Carolina First Steps to School Readiness Board of TrusteesGreenwood | Form 990 | $551,463FY2025 |
| Richland Library Friends and FoundationColumbia | Form 990 | $550,627FY2025 |
| Therapy Resource GroupFort Mill | Form 990 | $546,390FY2025 |
| Dream Preparatory Academy IncGreenville | Form 990 | $534,731FY2025 |
| South Carolina First Steps to School Readiness Board of TrusteesGreenwood | Form 990 | $521,496FY2025 |
| Wholespire IncColumbia | Form 990 | $516,582FY2025 |
| Tyger River Childrens Center IncMoore | Form 990 | $509,037FY2025 |
| Langston Foundation IncGreenville | Form 990 | $506,995FY2025 |
| Association of Cancer ExecutivesCharleston | Form 990 | $506,725FY2025 |
| Charleston Electrical Contractors Association IncNorth Charleston | Form 990 | $503,034FY2025 |
| Charleston HopeCharleston | Form 990 | $501,344FY2025 |
| South Carolina First Steps to School Readiness Board of TrusteesColumbia | Form 990 | $500,008FY2025 |
| Canine RescueNorth Augusta | Form 990 | $499,407FY2025 |
| South Carolina Workmens Compensation Educational AssociatiColumbia | Form 990 | $496,973FY2025 |
| Vine & Branches Home EducatorsMyrtle Beach | Form 990 | $482,885FY2025 |
| Southern Initiative of the Algebra Project IncSummerville | Form 990 | $479,217FY2025 |
| James E Clyburn Scholarship and Research FoundationColumbia | Form 990 | $468,223FY2025 |
| Parent Booster USA IncClover | Form 990 | $468,052FY2025 |
| J L Mann Athletic Booster Club IncGreenville | Form 990 | $454,376FY2025 |
| Everyblackgirl IncColumbia | Form 990 | $453,377FY2024 |
| Wando High School Band BoostersMount Pleasant | Form 990 | $449,958FY2025 |
| Healthy RoutinesColumbia | Form 990 | $449,820FY2025 |