| Waccamaw Elementary School PTOPawleys Island | Form 990-EZ | $67,991FY2025 |
| Springfield Elementary School PTACharleston | Form 990-EZ | $67,776FY2026 |
| Van Wyck Elementary School PTOLancaster | Form 990-EZ | $67,508FY2025 |
| Team Nelson IncCharleston | Form 990-EZ | $67,430FY2025 |
| Emergency Nurses AssociationCharleston | Form 990-EZ | $67,418FY2025 |
| RJ22 Enterprise IncSummerville | Form 990-EZ | $67,158FY2024 |
| George Briggs Association of Parents & TeachersFlorence | Form 990-EZ | $66,629FY2026 |
| Burgess Elementary PTOMyrtle Beach | Form 990-EZ | $66,286FY2025 |
| District 5 Foundation for Educational ExcellenceBallentine | Form 990-EZ | $65,788FY2025 |
| Parent Booster USA IncMoncks Corner | Form 990-EZ | $65,282FY2026 |
| Friends of the Georgetown Library IncGeorgetown | Form 990-EZ | $65,154FY2025 |
| Cherry Park Elementary School PTORock Hill | Form 990-EZ | $63,977FY2025 |
| Logan Jett Research Foundation IncTega Cay | Form 990-EZ | $63,227FY2025 |
| Easley Homeschool Athletics IncEasley | Form 990-EZ | $63,200FY2025 |
| Ninety Six Athletic Booster Club IncNinety Six | Form 990-EZ | $62,291FY2025 |
| Dixie High School Foundation IncDue West | Form 990-EZ | $62,062FY2026 |
| Laing Middle School PTOMount Pleasant | Form 990-EZ | $60,679FY2025 |
| Mauldin High School Athletic Booster ClubMauldin | Form 990-EZ | $59,979FY2025 |
| Captivating Montessori SchoolGreenwood | Form 990-EZ | $59,926FY2025 |
| Pleasant Knoll Middle School PTOFort Mill | Form 990-EZ | $59,402FY2025 |
| Center for Educational EquityGreenville | Form 990-EZ | $58,825FY2025 |
| Clover Leaders for Educational Advancement Foundation IncClover | Form 990-EZ | $58,533FY2026 |
| Rock N Roll RescueSullivans Island | Form 990-EZ | $58,461FY2025 |
| Wateree Hounds IncCamden | Form 990-EZ | $57,767FY2024 |
| Orangeburg County Community of CharacterOrangeburg | Form 990-EZ | $57,264FY2025 |
| Riverview Elementary School Parent Teacher OrganizationFort Mill | Form 990-EZ | $56,894FY2025 |
| Parent Booster USA IncCharleston | Form 990-EZ | $56,683FY2025 |
| Amazing Maasai Girls ProjectCharleston | Form 990 | $56,418FY2025 |
| Rocky Creek PTOLexington | Form 990-EZ | $56,198FY2026 |
| Catawba Trail Elementary Parent Teacher OrganizationElgin | Form 990-EZ | $56,061FY2025 |
| Bridges Preparatory School PTOBeaufort | Form 990-EZ | $55,622FY2024 |
| Learning Forward South CarolinaRock Hill | Form 990-EZ | $55,219FY2025 |
| Memminger School of Global StudiesCharleston | Form 990-EZ | $55,148FY2026 |
| Forest Acres Elementary Parent Teacher OrganizationEasley | Form 990-EZ | $55,074FY2026 |
| Philip Simmons High School Band BoosterCharleston | Form 990-EZ | $54,713FY2026 |
| Friends & Alumni Association of Palmetto High SchoolMullins | Form 990-EZ | $54,443FY2025 |
| May River High School Parent-Teacher OrganizationBluffton | Form 990-EZ | $54,408FY2025 |
| McLaurin Association of Parents and Teachers IncFlorence | Form 990-EZ | $54,400FY2025 |
| Heroes of the Low CountryBluffton | Form 990-EZ | $54,253FY2024 |
| Born to Read IncBeaufort | Form 990-EZ | $54,108FY2025 |
| Parent Booster USA IncFlorence | Form 990-EZ | $54,035FY2026 |
| Evergreen CollectiveMount Pleasant | Form 990-EZ | $53,964FY2024 |
| Meadow Glen Elementary School PTOLexington | Form 990-EZ | $53,826FY2025 |
| The Trident Club of South CarolinaLugoff | Form 990-EZ | $53,814FY2025 |
| Carolina Springs Elementary Parent Teacher OrganizationLexington | Form 990-EZ | $53,809FY2025 |
| Toadfish Outfitters Conservation Coalition IncCharleston | Form 990-EZ | $53,795FY2024 |
| South Carolina Congress of Parents and TeachersColumbia | Form 990-EZ | $53,613FY2026 |
| Parent Booster USA IncColumbia | Form 990-EZ | $53,204FY2026 |
| Friends of Kershaw County Library IncCamden | Form 990-EZ | $52,334FY2026 |
| Foundation for Professional DevelopmentWest Columbia | Form 990-EZ | $51,670FY2026 |