| The Willpower-IradaDarien | Form 990-EZ | $92,514FY2025 |
| Shield 23 Foundation IncGurnee | Form 990-EZ | $91,800FY2025 |
| Brenen Hornstein Autism Research and Education FoundationElk Grove Village | Form 990-EZ | $91,571FY2025 |
| Epilepsy Foundation of Southern IllinoisMount Vernon | Form 990-EZ | $91,015FY2025 |
| Shelby County Council on Aging IncShelbyville | Form 990-EZ | $88,846FY2025 |
| United Spinal Association Illinois ChapterPalos Heights | Form 990-EZ | $88,770FY2025 |
| Mary Diaz Pancreatic Cancer FundOak Park | Form 990-EZ | $86,349FY2025 |
| Chicago Lower Extremity Surgical FoundationChicago | Form 990-EZ | $86,239FY2023 |
| Cares for Cancer NFPChicago | Form 990-EZ | $84,844FY2025 |
| Everyone Reading IllinoisHillside | Form 990-EZ | $84,483FY2025 |
| Tessa Sutton FoundationDunlap | Form 990-EZ | $84,155FY2025 |
| Margaret Hackett Family Center NFPChicago | Form 990 | $82,860FY2025 |
| Kori Autism FoundationArlington Heights | Form 990-EZ | $82,140FY2024 |
| American Academy of Neurological & Orthopaedic SurgeryChicago | Form 990-EZ | $79,365FY2025 |
| Endpreeclampsia IncChicago | Form 990-EZ | $77,783FY2024 |
| Tragedy to Triumph FoundationLemont | Form 990-EZ | $77,264FY2025 |
| Joshuas Great Things FoundationO'Fallon | Form 990-EZ | $74,424FY2025 |
| Walter Boughton Foundation IncYorkville | Form 990-EZ | $71,750FY2025 |
| Illinois State Neurological SocietyQuincy | Form 990-EZ | $69,217FY2025 |
| Spine Institute for Quality Spine Iq IncPort Byron | Form 990-EZ | $67,809FY2024 |
| Cure MucolipidosisBelleville | Form 990-EZ | $67,567FY2024 |
| Harley Helping Hands IncBurr Ridge | Form 990-EZ | $64,172FY2025 |
| Crsa Clinical Robotic Surgery AssociationChicago | Form 990-EZ | $63,111FY2025 |
| Living LFS IncO'Fallon | Form 990-EZ | $60,198FY2024 |
| I Care International IncMorris | Form 990-EZ | $59,824FY2026 |
| Superhero Center for Autism IncPoplar Grove | Form 990-EZ | $57,538FY2025 |
| Foundation of the College of Diplomates of the AbpdDarien | Form 990-EZ | $57,042FY2025 |
| Midwest Sight Foundation NFPDecatur | Form 990-EZ | $56,445FY2025 |
| Illinois Society of Genetic ProfessionalsChicago | Form 990-EZ | $56,100FY2024 |
| Foundation for Dermatology EducationChicago | Form 990-EZ | $56,000FY2025 |
| Swing for Shimmer NFPMcHenry | Form 990-EZ | $54,082FY2025 |
| Massachusetts Maine and New Hampshire Rheumatology AssociationSchaumburg | Form 990-EZ | $53,131FY2022 |
| Lymphoma Is a LoserPekin | Form 990-EZ | $49,717FY2025 |
| Crop for a CauseBartlett | Form 990-EZ | $49,208FY2025 |
| Autism McLeanNormal | Form 990-N | No figure |
| Philippine Nurses Association of Illinois IncRomeoville | Form 990-N | No figure |
| Hugs in Hancock CountyCarthage | Form 990-N | No figure |
| Lets Save MaaCarol Stream | Form 990-N | No figure |
| God S Will and Wade CF FoundationBeecher City | Form 990-N | No figure |
| Patrick Grange Memorial Foundation NFPChicago | Form 990-EZ | $38,310FY2025 |
| Central Illinois Center for the Blind and Visually Impaired IncPeoria | Form 990 | $37,100FY2025 |
| National Basketball Association Physicians Society FoundationRosemont | Form 990-N | No figure |
| Hope Echoes CharitiesElmhurst | Form 990-N | No figure |
| Foundation for Sight LtdOrland Park | Form 990-N | No figure |
| Iec FoundationSchaumburg | Form 990-N | No figure |
| Warrior Nation Cancer FoundationVernon | Form 990-EZ | $32,627FY2025 |
| Royal Ball Run for Autism IncMilan | Form 990-EZ | $29,849FY2025 |
| Ards FoundationNorthbrook | Form 990-N | No figure |
| Latino Alzheimers Coalition for Advocacy Research and EducationChicago | Form 990-N | No figure |
| Lincoln Land Down Syndrome Support GroupSpringfield | Form 990-N | No figure |