| Can Community Health IncTampa | Form 990 | $506,024,240FY2025 |
| H Lee Moffitt Cancer Center and Research Institute IncTampa | Form 990 | $322,301,135FY2025 |
| H Lee Moffitt Cancer Ctr & Res Inst Life Time Cancer SCRN Ctr IncTampa | Form 990 | $173,244,422FY2025 |
| Care Resource Community Health Centers IncMiami | Form 990 | $138,789,620FY2025 |
| Foundcare IncWest Palm Beach | Form 990 | $56,778,252FY2024 |
| United Cerebral Palsy of Central Florida IncOrlando | Form 990 | $50,954,410FY2025 |
| H Lee Moffitt Cancer Center and Research Institute Foundation IncTampa | Form 990 | $41,320,097FY2025 |
| Central Florida Kidney Centers IncOrlando | Form 990 | $23,752,673FY2025 |
| Project Response IncMelbourne | Form 990 | $18,441,709FY2025 |
| United Cerebral Palsy Association of Miami IncHialeah | Form 990 | $17,795,369FY2025 |
| South Florida Public Media Group IncMiami | Form 990 | $15,660,344FY2025 |
| Els for Autism FoundationJupiter | Form 990 | $14,514,147FY2025 |
| Copd Foundation IncCoral Gables | Form 990 | $14,381,344FY2025 |
| Empower U IncMiami | Form 990 | $12,283,310FY2024 |
| Hemophilia Alliance Group Purchasing Organization IncClearwater | Form 990 | $10,882,096FY2024 |
| The Familial Hypercholesterolemia FoundationFernandina Beach | Form 990 | $10,718,916FY2025 |
| Positively U IncWinter Haven | Form 990 | $7,753,651FY2024 |
| Alzheimers Community Care IncWest Palm Beach | Form 990 | $7,702,857FY2025 |
| Global Virus Network IncTampa | Form 990 | $6,627,320FY2024 |
| Beyond the Spectrum IncLakewood Ranch | Form 990 | $6,298,522FY2025 |
| Third Wave Volunteers IncMiami | Form 990 | $6,199,112FY2024 |
| Care 4 U ManagementMiami | Form 990 | $5,226,375FY2024 |
| Sunrise Community of Southwest Florida IncMiami | Form 990 | $4,943,424FY2025 |
| Ah of Monroe County IncKey West | Form 990 | $4,818,421FY2024 |
| Unconditional Love IncorporatedMelbourne | Form 990 | $4,810,418FY2024 |
| Liga Contra El Cancer Inc League Against Cancer IncMiami | Form 990 | $4,737,649FY2025 |
| Andrews Research & Education Foundation IncGulf Breeze | Form 990 | $4,642,680FY2024 |
| Conklin Davis Center for the Visually Impaired IncDaytona Beach | Form 990 | $4,612,162FY2025 |
| Live Like Bella IncCoral Gables | Form 990 | $4,208,511FY2024 |
| Promise Fund of Florida IncWest Palm Beach | Form 990 | $4,189,322FY2024 |
| Libbys Legacy Breast Cancer FoundationOrlando | Form 990 | $3,984,930FY2025 |
| Capstone Adaptive Learning and Therapy Centers IncPensacola | Form 990 | $3,979,538FY2025 |
| Florida Society of Clinical Oncology IncRiverview | Form 990 | $3,795,093FY2024 |
| Community Access to Child Health of Brevard IncRockledge | Form 990 | $3,647,817FY2025 |
| Who We Play for IncMelbourne | Form 990 | $3,598,918FY2025 |
| The Brain Tumor Network IncPonte Vedra | Form 990 | $3,530,806FY2025 |
| American Academy of Optometry Foundation IncWinter Park | Form 990 | $3,442,243FY2025 |
| Fidec IncCoral Gables | Form 990 | $3,192,675FY2025 |
| Parkinson Research Foundation IncSarasota | Form 990 | $3,163,049FY2025 |
| Northeast Florida AIDS Network IncJacksonville | Form 990 | $2,925,339FY2025 |
| Caps International IncCoral Gables | Form 990 | $2,888,715FY2025 |
| Force-Facing Our Risk of Cancer EmpoweredTampa | Form 990 | $2,642,483FY2025 |
| American Association of Kidney Patients IncTampa | Form 990 | $2,435,680FY2025 |
| Walker Cancer Research Institute IncBoynton Beach | Form 990 | $2,256,783FY2024 |
| American Committee for Lehosheet YadBiscayne Park | Form 990 | $2,207,130FY2024 |
| Mana-Sota Lighthouse for the Blind IncSarasota | Form 990 | $2,038,425FY2025 |
| Foundation for Dreams IncBradenton | Form 990 | $1,819,654FY2025 |
| Gildas Club of South Florida IncFort Lauderdale | Form 990 | $1,694,003FY2025 |
| American Society for Preventive CardiologyJacksonville | Form 990 | $1,623,329FY2023 |
| Pan American League of Associations for RheumatologyMiami | Form 990 | $1,602,494FY2024 |