| Population Services InternationalWashington | Form 990 | $306,308,594FY2024 |
| Patient Access Network FoundationWashington | Form 990 | $230,809,794FY2025 |
| Neighborhood Reinvestment CorpWashington | Form 990 | $179,198,962FY2025 |
| National Park FoundationWashington | None required | $173,752,964FY2025 |
| Community Partnership for the Prevention of HomelessnessWashington | Form 990 | $146,271,915FY2025 |
| Marys Center for Maternal and Child Care IncWashington | Form 990 | $98,876,368FY2025 |
| Share Our StrengthWashington | Form 990 | $89,894,889FY2025 |
| Hudson Institute IncWashington | Form 990 | $67,049,361FY2025 |
| Voter Registration ProjectWashington | Form 990 | $65,646,323FY2024 |
| National Association of Childrens Hospital and Related InstitutionsWashington | Form 990 | $64,966,463FY2025 |
| National Association of County and City Health OfficialsWashington | Form 990 | $62,267,559FY2025 |
| American Independent FoundationWashington | Form 990 | $58,642,994FY2024 |
| UnidosusWashington | Form 990 | $53,467,392FY2025 |
| Some IncWashington | Form 990 | $43,400,634FY2024 |
| New America FoundationWashington | Form 990 | $37,233,867FY2024 |
| Rural Community Assistance Partnership IncorporatedWashington | Form 990 | $36,849,641FY2025 |
| American Society of Nephrology IncWashington | Form 990 | $36,768,596FY2025 |
| National Childrens Alliance IncWashington | Form 990 | $36,455,844FY2025 |
| The Albert B Sabin Vaccine Institute IncWashington | Form 990 | $35,914,020FY2024 |
| National Partnership for Women and Families IncWashington | Form 990 | $35,315,157FY2025 |
| Improving Economies for Stronger CommunitiesWashington | Form 990 | $32,318,340FY2024 |
| National Association for Equal Opportunity in Higher EducationWashington | Form 990 | $31,414,820FY2023 |
| DC Central Kitchen IncWashington | Form 990 | $31,132,475FY2025 |
| Council for Advancement and Support of EducationWashington | Form 990 | $30,988,312FY2025 |
| Federalist Society for Law & Public Policy StudiesWashington | Form 990 | $30,054,748FY2025 |
| The One CampaignWashington | Form 990 | $29,460,640FY2024 |
| National Association of Independent Schools IncWashington | Form 990 | $27,311,841FY2025 |
| American Society for Engineering EducationWashington | Form 990 | $26,373,548FY2025 |
| The Executive Leadership Council IncWashington | Form 990 | $24,892,688FY2024 |
| Reproductive Freedom for All FoundationWashington | Form 990 | $24,241,361FY2025 |
| National Womens Law CenterWashington | Form 990 | $24,153,153FY2025 |
| UsagingWashington | Form 990 | $24,038,189FY2025 |
| North American Securities Administrators Association IncWashington | Form 990 | $23,115,348FY2024 |
| Heart Rhythm Society IncWashington | Form 990 | $23,043,846FY2025 |
| Council of Independent CollegesWashington | Form 990 | $22,332,825FY2025 |
| The Washington Center for Internships and Academic SeminarsWashington | Form 990 | $21,079,197FY2024 |
| Boys & Girls Clubs of Greater Washington IncWashington | Form 990 | $20,414,806FY2024 |
| The Computing Research Association IncWashington | Form 990 | $20,254,835FY2025 |
| Service Corps of Retired Executives AssociationWashington | Form 990 | $20,139,866FY2025 |
| National Association of College andWashington | Form 990 | $20,033,806FY2025 |
| Jubilee Housing IncWashington | Form 990 | $19,093,136FY2024 |
| Lawyers Committee for Civil Rights Under LawWashington | Form 990 | $18,494,672FY2024 |
| American Society for Reproductive MedicineWashington | Form 990 | $16,725,749FY2025 |
| Edlavitch Jewish Community Center of Washington DC IncWashington | Form 990 | $16,590,808FY2025 |
| Reporters Committee for Freedom of the PressWashington | Form 990 | $15,862,155FY2025 |
| Legal Aid Society of the District of ColumbiaWashington | Form 990 | $15,789,338FY2025 |
| National Governors Association Center for Best PracticesWashington | Form 990 | $15,721,713FY2025 |
| The Fund for American StudiesWashington | Form 990 | $15,597,054FY2025 |
| Links Foundation IncWashington | Form 990 | $15,558,865FY2025 |
| National Law Enforcement Officers Memorial Fund IncWashington | Form 990 | $15,447,648FY2024 |